| Nomenclature |
CBH-rnu/Arc |
| Product code |
CBHNU |
| Strain Description |
Mutant inbred |
| Coat Colour |
Black hooded (a, B, C, h) |
| MHC Haplotype |
RT1c |
- Homozygotes have little or no hair and are athymic.
- Heterozygotes have hair and functioning thymus.
- Prone to dust in their eyes as no eyelashes.
- Similar dysgenesis to nude mutation in mice.
- Cell mediated immunity greatly reduced or absent with a marked reduction of T-lymphocyte function.
- Extremely susceptible to infection with Clostridium piliforme.
- Housed in an isolator.
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