| Nomenclature |
NOD.CB17-Prkdcscid/Arc |
| Product code |
NODSCID |
| Strain Description |
Mutant inbred |
| Coat Colour |
Albino (A/A Tyrc/Tyrc) |
| MHC Haplotype |
H2Kg7 |
| Complement Factor |
C5 deficient |
- Prkdcscid – autosomal recessive, protein kinase, DNA activated, catalytic polypeptide.
- No endogenous T- or B- lymphocyte function.
- Develops high incidence of thymoma with age and old mice can develop inclusion body nephropathy.
- Used for the delineation of the role of T cell subsets and auto-antibodies in diabetes.
- Housed in an isolator.
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