A/J

Health Report Area 3a

Nomenclature A/JArc
Product code AJ
Strain Description Inbred
Coat Colour Albino (a/a Tyrp1b/Tyrp1b Tyrc/Tyrc)
MHC Haplotype H2Ka
Complement Factor C5 deficient
  • Used in research on CD antigens, antigen receptors and histocompatibility markers.
  • High social dominance of males in competition for females.
  • High spontaneous incidence of lung adenomas and mammary tumours in breeding females.
  • Congenital defects include cleft-lip/palate and polydactyly at a prevalence of up to 10%.
  • Incidence of nephritis and amyloidosis nearly 100% at 15 months.
  • Low aggression, low responder in general (activity, alcohol, anaesthetics, metabolism).
  • Hearing loss, blindness.

AJ