|JAX stock number
- Good breeding performance.
- Susceptible to the development of atheromatous lesions after 20 weeks on high fat diets.
- Develops non-insulin dependent diabetes mellitus and hypertension when fed a high/fat, high simple-carbohydrate diet.
- Glucose intolerance is due to spontaneous mutation in Nicotinamide Nucleotide Transhydrogenase (Nnt).
- Generally refractory to many tumours and to many infectious agents.
- Congenital abnormalities include microphthalmia, corneal opacities, anophthalmia and hydrocephalus (Smith, R.S., Roderick, T.H. and Sundberg, J.P., 1994).
- Susceptible to imperforate vaginas and mucometra.
- White spotting commonly observed in pigmentation.
- Aggressiveness observed in male stock from 6 weeks of age and female breeders.
- Fighting amongst males increases when cohorts are divided intosm aller groups.
- Barbering and ulcerative dermatitis observed.
- See www.jax.org for more strain information.
- These mice are sold subject to The Jackson Laboratory’s Conditions of Use and also the Australian Patent Number (2004268530). Information regarding conditions of use is available at: http://jaxmice.jax.org/cou/index.html.