C3H/HeJ

Nomenclature C3H/HeJArc
Product code C3H
JAX stock number 000659
Strain Description Inbred
Coat Colour Agouti (A/A)
MHC Haplotype H2Kk
Complement Factor C5 normal
  • Used as a general purpose strain in a wide variety of research areas including cancer, infectious disease, sensorineural, and cardiovascular biology research.
  • Blindness by weaning age.
  • High incidence of hepatomas.
  • Average breeding performance.
  • Typically C3H/HeJArc are unresponsive to lipopolysaccharide (LPS) due to a B-cell deficiency (Anderson and Ostermann, 1980).
  • Highly susceptible to infection by Gram negative bacteria.
  • Spontaneous corneal opacities.
  • Retina lack photoreceptors.
  • Hearing normal.
  • Alopecia areata.
  • Cardiac mineralisation/calcinosis.
  • See www.jax.org for more strain information.
  • These mice are sold subject to The Jackson Laboratory’s Conditions of Use and also the Australian Patent Number (2004268530). Information regarding conditions of use is available at: http://jaxmice.jax.org/cou/index.html.

Health Report

 

C3H/HeJ